Presenting all preclinical and clinical information available on genetically engineered toxins this unique single-source reference provides the most up-to-date methods and practical examples for conducting clinical studies in toxin molecular biology. ;Reviewing difficult problems and their solutions Genetically Engineered Toxins discusses techniques for clo;ning expressing and purifying recombinant toxins and genetically modified recombinant toxins; documents structure-function relationships in toxins including comparative information; supplies theory and illustrations of chimeric toxins; delineates the preclinical assessments of new reagents; and summarizes approaches to drug design. ;With over 1100 literature citations Genetically Engineered Toxins is an invaluable resource for biochemists molecular biologists biotechnologists pharmacologists toxicologists X-ray crystallographers enzymologists oncologists hematologists immunologists rheumatologists botanists and graduate-level students in molecular biology biotechnology and clinical oncology courses. Language: English